Scientists have discerned how a single key enzyme differentiates and dynamically binds both DNA and RNA as part of HIV's fierce attack on host cells. The new finding results from a study led by Xiaowei Zhuang of Harward University and Stuart Le Grice of the National Cancer Institute. The researchers have revealed that the enzyme they studied, reverse transcriptase (RT), is already the target of two of the three major classes of existing anti-HIV drugs.

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